CHAMBERSBURG, PA., Oct. 15, 1853.

  To the Editor of the National Era:

  If you think the following account of the representation of "Uncle Tom's Cabin" at the National Theatre, Philadelphia, will interest any of your readers, you are at liberty to publish it. It is an extract of a letter received by me a few days since, from an intelligent gentleman of that city:

  "I went last night to see 'Uncle Tom's Cabin,' at the National Theatre. It is worth far more, to the philanthropist, to see the audience it draws, than to witness the performance. High and low are assembled nightly in crowds, and thus the ears and hearts of a large class are reached, who have heretofore been ignorant and cruelly bitter in their prejudices against color. The piece, as dramatized, acts well, and is full of incident and pathos. Its tone is extremely religious, and well calculated to produce a powerful and beneficial impression on the moral nature, if any piece that ever was played on the stage can be said to have such a tendency. In sentiment it is, as you may suppose, thoroughly abolition, and cannot but lend essential aid to the cause we have so much at heart. There was much applause manifested at the expression of the sentiments of love of liberty and equality of rights, (among men, whatever their color,) and also at those parts wherein the slave is assisted and rescued, and the slave hunter and dealer foiled—as in the escape of Eliza Harris across the ice, and that of George Harris and the rest, with Phineas Fletcher at their head. As a general thing, there was much more deep feeling than boisterous applause, owing to the religious and pathetic character of the play. Tears were shed freely, and in almost every scene; and I must confess that I was affected a little more strongly than I desired to be. All the minutiae of the book are brought out upon the stage; and if they are faithfully represented, I have obtained from the representation a better idea that I ever had of 'life among the lowly.' The slave dealer, with his beastly, vulgar, and familiar manners and his heavy whip; the mean slave-catcher, the auctioneer of human chattels, the slave mart, and in the centre the block two or three feet high for the chattel to stand on, so that the bidders may the more conveniently feel the limbs and flesh of the article bid for—all were presented in such a vivid manner that one will not soon forget them. I incline to think that kidnapping is going to be rather unpopular here in future, and that the cause of Abolition is going to grow in favor with the masses. God speed a consummation so devoutly to be wished! 'Uncle Tom's Cabin' has been running more than three weeks, and I had to go twice before I could get a seat this week. How much longer it will run, no one knows."