The Liberator of last week reports that the sixtieth thousand of this work was about to be issued by the publisher in Boston, in the eleventh week of its publication. It is a fact altogether unprecedented in the history of book-making in this country, and is a strong evidence of the strength of the feeling existing in the North on the subject of Slavery. It is a fair computation, though probably even below the mark, that the book has already been read by half a million of people, and by it the attention of very many has been aroused to the contemplation of the horrors of the system, and their own responsibility in regard to it. Both as an effect and a cause, 'Uncle Tom's Cabin' will leave its mark on this year, notwithstanding Baltimore Conventions and Compromise Resolutions. Nor is it the first time a great work has been done in the Anti-Slavery Cause by a single book. The last and the effectual blow that was struck for West India Emancipation was by a pamphlet.

  The prospect of a wide circulation of 'Uncle Tom's Cabin' in England is also very promising. We learn that an edition has just been issued in London, which is selling rapidly at about sixty-two cents of our money.